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ADRM1 monoclonal antibody

货号: MB10503

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB10503

Product Name :ADRM1 monoclonal antibody

Swiss-Prot :Q16186

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-F,IHC-P,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background :Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 42 kDa; Observed MW: 42 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ARM1; ARM-1; GP110

Immunogen :A synthetic peptide of human ADRM1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of ADRM1 in K562, Hela lysates using ADRM1 antibody.

Immunocytochemistry analysis of ADRM1 in Hela using ADRM1 antibody,and DAPI