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Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) monoclonal antibody

货号: MB10414

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10414

Product Name :Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) monoclonal antibody

Swiss-Prot :P04626

Host :Rabbit

Reactivity :Human

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 138 kDa; Observed MW: 180 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ErbB 2

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of PhosohoErbB 2 /EGFR in Hela lysates using PhosohoErbB 2/EGFR antibody.