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CRTC3 monoclonal antibody

货号: MB10329

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB10329

Product Name :CRTC3 monoclonal antibody

Swiss-Prot :Q6UUV7

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,ICC/IF

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200

Background :Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small inTine, spleen and stomach.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 67 kDa; Observed MW: 78 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TORC3; FLJ21868; CRTC3

Immunogen :A synthetic peptide of human CRTC3

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of CRTC3 in Hela using CRTC3 antibody,and DAPI.

免疫沉淀（IP）