产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

RAB4A monoclonal antibody

货号: MB0161

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0161

Product Name :RAB4A monoclonal antibody

Swiss-Prot :P20338

Host :Mouse

Reactivity :Human,Mouse,Monkey

Applications :WB,IHC-P,FC

Application_all :WB: 1:1000 ICC: 1:100~300

Background :The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies, exhibits 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possiblity that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab family have been identified, each of which is found at a particular stage of a membrane transport pathway.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of RAB4A and does not cross-react with related proteins

BiowMW :Predicted band size:24KDa Observed band size:30KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ras-related protein Rab-4A; RAB4

Immunogen :Recombinant full length Human RAB4A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of RAB4A in Rat stomach, Mouse brain, Hela & MCF7 cell lysates and using RAB4A antibody (1:1000 diluted) .

Immunohistochemistry analysis of paraffin-embedded Human colon using CKII alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.