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CD31/PECAM-1 monoclonal antibody

货号: MB0122

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB0122

Product Name :CD31/PECAM-1 monoclonal antibody

Swiss-Prot :P16284

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1:1000

Background :CD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells and endothelial cells, and modulates cell adhesion, endothelial cell migration and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical stress or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain containing binding partners such as PI3-kinase, SHIP, PLCγ and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD31/PECAM-1 mAb detects endogenous levels of CD31 protein.

BiowMW :Predicted band size:130KDa Observed band size:130KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD31; PECAM1

Immunogen :Recombinant full length Human CD31.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PECAM1 antibody in THP-1 cell lysate using CD31/PECAM-1 antibody (1:1000 diluted) .

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