产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

CBR1 monoclonal antibody

货号: MB0121

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0121

Product Name :CBR1 monoclonal antibody

Swiss-Prot :P16152

Host :Mouse

Reactivity :Human

Applications :WB ICC

Application_all :WB:1:1000 ICC:1:100

Background :Carbonyl reductase is one of several monomeric,NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds.This enzyme is widely distributed in human tissues. Another carbonyl reductase gene,CRB3,lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CBR1 mAb detects endogenous levels of CBR1 protein.

BiowMW :Predicted band size:30KDa Observed band size:30KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9 ketoreductase; Prostaglandin 9-ketoreductase; Prostaglandin E(2) 9 reductase; Prostaglandin-E(2) 9-reductase; SDR21C1; CBR; hCBR1; SDR21C1

Immunogen :Recombinant full length Human CBR1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CBR1 in Hela, A431 & MDA-MB-468 cell lysates using CBR1 antibody (1:1000 diluted) .