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Calumenin (C-terminus) monoclonal antibody

货号: MB0120

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB0120

Product Name :Calumenin (C-terminus) monoclonal antibody

Swiss-Prot :O43852

Host :Mouse

Reactivity :Human,Mouse

Applications :WB

Application_all :WB:1:1000

Background :Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and/or wound healing by acting in an autocrine or paracrine manner.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Calumenin (C-terminus) mAb detects endogenous levels of Calumenin protein.

BiowMW :Predicted band size:37KDa Observed band size:45KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Crocalbin; IEF SSP 9302; CALU

Immunogen :Synthetic peptide, corresponding to amino acids C-terminus of Human Calumenin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CALU in SW480, mouse intestine &A431 cell lysates and using CALU antibody (1:1000 diluted) .

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）