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AURKA (N-terminus) monoclonal antibody

货号: MB0116

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0116

Product Name :AURKA (N-terminus) monoclonal antibody

Swiss-Prot :O14965

Host :Mouse

Reactivity :Human,Monkey

Applications :WB

Application_all :WB:1:200~1000

Background :Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AURKA (N-terminus) mAb detects endogenous levels of AURKA protein.

BiowMW :Predicted band size:46KDa Observed band size:46KDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Epigenetic Writers and Erasers of Histone H3,

Alternative Name :Aurora kinase A; Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A; AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6

Immunogen :Recombinant full length Human AURKA (N-terminus).

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of AURKA in HL60, SW480, MCF7, 293, COS7 & HepG2 cell lysates and using AURKA antibody (1:200 diluted) .