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AMACR (C-terminus) monoclonal antibody

货号: MB0099

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0099

Product Name :AMACR (C-terminus) monoclonal antibody

Swiss-Prot :Q9UHK6

Host :Mouse

Reactivity :Rat

Applications :WB ICC

Application_all :WB: 1:1000 ICC: 1:50~200

Background :P504S, also known as AMACR (a-methylacyl-CoA racemase), 2-methylacyl-CoA racemase or RACE, is an enzyme belonging to the caiB/baiF CoA-transferase family. Localizing to the peroxisome and mitochondrion, P504S plays a role in the metabolism of branched-chain fatty acids and bile acid intermediates. More specifically, P504S catalyzes the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers which can then be degraded by peroxisomal b-oxidation. Mutations in the gene encoding P504S can lead to AMACR deficiency, a disease characterized by increased concentrations of pristanic acid that is associated with adult onset sensory motor neuropathy.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of AMACR and does not cross-react with related proteins

BiowMW :Predicted band size:42KDa Observed band size:42KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; AMACR

Immunogen :Synthetic peptide, corresponding to the C-terminus of Human AMACR.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of AMACR (C-terminus) antibody in Rat Liver lysates using AMACR (C-terminus) antibody (1:1000 diluted) .

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）