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Securin polyclonal antibody

货号: BZ16895

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16895

Product Name :Securin polyclonal antibody

Swiss-Prot :O95997/Q6IAL9

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,ICC/IF,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 22 kDa; Observed MW: 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PTTG1; EAP1; PTTG; TUTR1; Securin; Esp1-associated protein; Pituitary tumor-transforming gene 1 protein; Tumor-transforming protein 1; hPTTG

Immunogen :A synthesized peptide derived from human Securin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Securin in HeLa lysates using Securin antibody.