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BUBR1 polyclonal antibody

货号: BZ16811

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16811

Product Name :BUBR1 polyclonal antibody

Swiss-Prot :O60566

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100

Background :Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 120 kDa; Observed MW: 120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1

Immunogen :A synthesized peptide derived from human BubR1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of BubR1 in HepG2 lysates using BUBR1 antibody.