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Integrin alpha 5 polyclonal antibody

货号: BZ16736

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16736

Product Name :Integrin alpha 5 polyclonal antibody

Swiss-Prot :P08648

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ICC/IF,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 115 kDa; Observed MW: 150 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e

Immunogen :A synthesized peptide derived from human Integrin alpha 5

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Integrin alpha 5 in mouse heart lysates using Integrin alpha 5 antibody.

Immunofluorescence analysis of Integrin alpha 5 in MCF-7 using Integrin alpha 5 antibody.