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Phospho-Raf1 (Ser259) polyclonal antibody

货号: BZ16727

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BZ16727

Product Name :Phospho-Raf1 (Ser259) polyclonal antibody

Swiss-Prot :P04049

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 73 kDa; Observed MW: 73 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1

Immunogen :A synthesized peptide derived from human Phospho-Raf1 (S259)

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Raf1 in 293T lysates; 293T lysates treated with Okadaic Acid + Calyculin A using Phospho-Raf1 antibody.

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