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Fibrillarin polyclonal antibody

货号: BZ16628

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16628

Product Name :Fibrillarin polyclonal antibody

Swiss-Prot :P22087

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ICC/IF,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :Fibrillarin is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 34 kDa; Observed MW: 34 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FIB; FLRN; Nop1; RNU3IP1

Immunogen :A synthesized peptide derived from human Fibrillarin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Fibrillarin in HepG2 lysates using Fibrillarin antibody.

Immunohistochemistry analysis of paraffin-embedded Human testis using Fibrillarin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of Fibrillarin in Hela using Fibrillarin antibody.