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HP1 alpha polyclonal antibody

货号: BZ16624

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16624

Product Name :HP1 alpha polyclonal antibody

Swiss-Prot :P45973

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ICC/IF,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 22 kDa; Observed MW: 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha

Immunogen :A synthesized peptide derived from human HP1 alpha

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HP1 alpha in SH-SY5Y lysates using HP1 alpha antibody.

免疫沉淀（IP）