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Phospho-Src (Tyr419) polyclonal antibody

货号: BZ16612

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16612

Product Name :Phospho-Src (Tyr419) polyclonal antibody

Swiss-Prot :P12931

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,FC

Application_all :WB: 1/500-1/1000 FC: 1/50-1/100

Background :Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 60 kDa; Observed MW: 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src

Immunogen :A synthesized peptide derived from human Phospho-Src (Y419)

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Src in A431 lysates treated with pervanadate using Phospho-Src antibody.

免疫沉淀（IP）