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Interferon alpha/beta Receptor 1 polyclonal antibody

货号: BZ16610

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16610

Product Name :Interferon alpha/beta Receptor 1 polyclonal antibody

Swiss-Prot :P17181

Host :Rabbit

Reactivity :Human

Applications :WB,IP,FC

Application_all :WB: 1/500-1/1000 IP: 1/20 FC: 1/50-1/100

Background :Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 64 kDa; Observed MW: 90,130 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IFNAR1; IFNAR; Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1

Immunogen :A synthesized peptide derived from human IFNAR1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of IFNAR1 in K562 lysates using Interferon alpha/beta Receptor 1 antibody.