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Phospho-eIF4E (Ser209) polyclonal antibody

货号: BZ16602

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BZ16602

Product Name :Phospho-eIF4E (Ser209) polyclonal antibody

Swiss-Prot :P06730

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background :eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 25 kDa; Observed MW: 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein

Immunogen :A synthesized peptide derived from human Phospho-eIF4E (S209)

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of eIF4E in HEK293 lysates; mouse spleen lysates using Phospho-eIF4E antibody.

Immunohistochemistry analysis of paraffin-embedded mouse kidney using Phospho-eIF4E antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.