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Bak polyclonal antibody

货号: BZ16594

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16594

Product Name :Bak polyclonal antibody

Swiss-Prot :Q16611

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC-P,ICC/IF,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 23 kDa; Observed MW: 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7

Immunogen :A synthesized peptide derived from human Bak

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Bak in HeLa lysates using Bak antibody.

Immunohistochemistry analysis of paraffin-embedded mouse liver using Bak antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of Bak in Hela using Bak antibody.