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LEF1 polyclonal antibody

货号: BZ16587

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16587

Product Name :LEF1 polyclonal antibody

Swiss-Prot :Q9UJU2

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ICC/IF,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 44 kDa; Observed MW: 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha

Immunogen :A synthesized peptide derived from human LEF1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LEF1 in Jurkat lysates using LEF1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human spleen using LEF1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.