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LRP1 polyclonal antibody

货号: BZ16570

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BZ16570

Product Name :LRP1 polyclonal antibody

Swiss-Prot :Q07954

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ICC/IF,IP,FC

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background :Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.Functions as a receptor for Pseudomonas aeruginosa exotoxin A.

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 505 kDa; Observed MW: 85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :A2MR; alpha 2MR; Alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5

Immunogen :A synthesized peptide derived from human LRP1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LRP1 in U87-MG and Hela lysates using LRP1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human liver carcinoma using LRP1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.