产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

p300 polyclonal antibody

货号: BZ16469

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16469

Product Name :p300 polyclonal antibody

Swiss-Prot :Q09472

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :ICC/IF,WB,IHC-F,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 264 kDa; Observed MW: 300 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300

Immunogen :Synthesized peptide derived from the Internal region of human p300.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of p300 in HELA, 293T, 823AV lysates using p300 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breastcancer using p300 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.