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MSK1 polyclonal antibody

货号: BZ16449

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16449

Product Name :MSK1 polyclonal antibody

Swiss-Prot :O75582

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,ICC/IF,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 90 kDa; Observed MW: 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL

Immunogen :Synthesized peptide derived from human MSK1 around the non-phosphorylation site of T581.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of MSK1 in 293 lysates using MSK1 antibody.

Immunofluorescence analysis of MSK1 in HUVEC using MSK1 antibody. The picture on the right is blocked using the synthesized peptide.