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FAK polyclonal antibody

货号: BZ16437

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16437

Product Name :FAK polyclonal antibody

Swiss-Prot :Q05397

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background :This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 119 kDa; Observed MW: 119 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Immunogen :The antiserum was produced against synthesized peptide derived from human FAK. AA range:373-422

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of FAK in various lysates using FAK antibody.

Western blot analysis of FAK in HT-29 lysates using FAK antibody.