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Claudin 1 polyclonal antibody

货号: BZ16429

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16429

Product Name :Claudin 1 polyclonal antibody

Swiss-Prot :O95832

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :The claudin family is composed of 23 integral membrane proteins, and their expression, which varies among tissue types, may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer. Claudin-1 is expressed primarily in keratinocytes and normal mammary epithelial cells, but is absent or reduced in breast carcinomas and breast cancer cell lines.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 23 kDa; Observed MW: 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein

Immunogen :The antiserum was produced against synthesized peptide derived from human Claudin 1. AA range:162-211

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Claudin 1 in Hela lysates using Claudin 1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using Claudin 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.