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CMKLR1 polyclonal antibody

货号: BZ16428

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16428

Product Name :CMKLR1 polyclonal antibody

Swiss-Prot :Q99788

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 42 kDa; Observed MW: 42 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DEZ; RVER1; ChemR23; CHEMERINR

Immunogen :The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of CMKLR1 in various lysates using CMKLR1 antibody.

免疫沉淀（IP）