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Phospho-Cardiac Troponin I (Ser22/Ser23) polyclonal antibody

货号: BZ16417

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BZ16417

Product Name :Phospho-Cardiac Troponin I (Ser22/Ser23) polyclonal antibody

Swiss-Prot :P23693

Host :Rabbit

Reactivity :Mouse,Rat

Applications :WB,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background :Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 24 kDa; Observed MW: 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I

Immunogen :The antiserum was produced against synthesized peptide derived from rat TNNI3 around the phosphorylation site of Ser22 and Ser23. AA range:5-54

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Cardiac Troponin I in SH-SY5Y lysates using Phospho-Cardiac Troponin I antibody.

EnzymeLinked Immunosorbent Assay for Immunogen Phospho-peptide and NonPhospho-peptide , using TNNI3 antibody.