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Phospho-ErbB 2 (Tyr1221/Tyr1222) polyclonal antibody

货号: BZ16411

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16411

Product Name :Phospho-ErbB 2 (Tyr1221/Tyr1222) polyclonal antibody

Swiss-Prot :P04626

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,IP,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 ELISA: 1/10000

Background :This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 138 kDa; Observed MW: 180 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340

Immunogen :The antiserum was produced against synthesized peptide derived from human HER2 around the phosphorylation site of Tyr1221/Tyr1222. AA range:1191-1240

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-ErbB 2 in various lysates using Phospho-ErbB 2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma, using HER2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.