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Phospho-JAK2 (Tyr1007) polyclonal antibody

货号: BZ16410

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BZ16410

Product Name :Phospho-JAK2 (Tyr1007) polyclonal antibody

Swiss-Prot :O60674

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background :Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 131 kDa; Observed MW: 131 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Immunogen :The antiserum was produced against synthesized peptide derived from human JAK2 around the phosphorylation site of Tyr1007. AA range:981-1030

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-JAK2 in NIH3T3 lysates using Phospho-JAK2 antibody.