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Phospho-EGFR (Tyr1092) polyclonal antibody

货号: BZ16408

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BZ16408

Product Name :Phospho-EGFR (Tyr1092) polyclonal antibody

Swiss-Prot :P00533

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background :EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 134 kDa; Observed MW: 140-160 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Immunogen :The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1092. AA range:1061-1110

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-EGFR in various lysates using Phospho-EGFR antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma, using EGFR antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.