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Cleaved-Caspase 1 polyclonal antibody

货号: BZ16404

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BZ16404

Product Name :Cleaved-Caspase 1 polyclonal antibody

Swiss-Prot :P29466

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,ICC/IF,IHC-F,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 45 kDa; Observed MW: 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Immunogen :The antiserum was produced against synthesized peptide derived from human Cleaved-Caspase 1. AA range:161-210

Conjugate :Unconjugated

Modification :Cleaved

Western blot analysis of Cleaved-Caspase 1 in NIH3T3 lysates using Cleaved-Caspase 1 antibody.

Human amniotic mesenchymal stem cell-conditioned medium inhibited LPS-induced cell injury and inflammation by modulating CD14/TLR4-mediated signaling pathway in monocytes

JournalMOLECULAR IMMUNOLOGY

ApplicationWB

IF4.174

SpeciesHuman

PMID37087900