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Phospho-Smad3 (Ser425) polyclonal antibody

货号: BZ16381

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BZ16381

Product Name :Phospho-Smad3 (Ser425) polyclonal antibody

Swiss-Prot :P84022

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :ICC/IF,WB,IHC-F,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 48 kDa; Observed MW: 58 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

Immunogen :The antiserum was produced against synthesized peptide derived from human Smad3 around the phosphorylation site of Ser425. AA range:376-425

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Smad3 in various lysates using Phospho-Smad3 antibody.

Mitochondrial fusion induced by transforming growth factor-β1 serves as a switch that governs the metabolic reprogramming during differentiation of regulatory T cells

JournalRedox Biology

ApplicationWB

IF10.787

SpeciesMouse

PMID37116255