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Phospho-Chk2 (Thr68) polyclonal antibody

货号: BZ16375

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16375

Product Name :Phospho-Chk2 (Thr68) polyclonal antibody

Swiss-Prot :O96017

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,ICC/IF,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 61 kDa; Observed MW: 61 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2

Immunogen :The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68. AA range:35-84

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Chk2 in Jurkat treated with UV lysates using Phospho- Chk2 antibody.