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Bcl6 polyclonal antibody

货号: BZ16342

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16342

Product Name :Bcl6 polyclonal antibody

Swiss-Prot :P41182

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :ICC/IF,WB,IHC-F,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFκB expression, thereby inhibiting NFκB-mediated cellular functions.HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs).

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 79 kDa; Observed MW: 79 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51

Immunogen :The antiserum was produced against synthesized peptide derived from the Internal region of human BCL6. AA range:271-320

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Bcl6 in 293 lysates using Bcl6 antibody.