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ABCG2 polyclonal antibody

货号: BZ16338

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BZ16338

Product Name :ABCG2 polyclonal antibody

Swiss-Prot :Q9UNQ0

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background :ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 72 kDa; Observed MW: 72 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338

Immunogen :The antiserum was produced against synthesized peptide derived from human ABCG2. AA range:289-338

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of ABCG2 in various lysates using ABCG2 antibody.