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Phospho-IKK alpha/beta (Ser176/Ser177) polyclonal antibody

货号: BZ16321

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16321

Product Name :Phospho-IKK alpha/beta (Ser176/Ser177) polyclonal antibody

Swiss-Prot :O15111

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1/500-1/1000

Background :Plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKβ (Ser176 and Ser180 in IKKα), which causes conformational changes, resulting in kinase activation.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 85 kDa; Observed MW: 85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B

Immunogen :Synthetic peptide of human CHUK

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-IKK alpha/beta in 3T3 lysates using Phospho-IKK alpha/beta antibody.

Licoricesaponin G2 ameliorates bleomycin-induced pulmonary fibrosis via targeting TNF-α signaling pathway and inhibiting the epithelial-mesenchymal transition

JournalFrontiers in Pharmacology

ApplicationWB

IF4.4

SpeciesMouse,Human

PMID39301567