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Phospho-Estrogen Receptor alpha (Ser118) polyclonal antibody

货号: BZ16290

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BZ16290

Product Name :Phospho-Estrogen Receptor alpha (Ser118) polyclonal antibody

Swiss-Prot :P03372

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Background :ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 66 kDa; Observed MW: 66 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha

Immunogen :Synthetic peptide of human ESR1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Estrogen Receptor alpha in MDAMB435 lysates using Phospho-Estrogen Receptor alpha antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Estrogen Receptora antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Immunofluorescence analysis of Phospho-Estrogen Receptor alpha in MCF-7 cells using Estrogen Receptora antibody.