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Phospho-PTEN (Ser380) polyclonal antibody

货号: BZ16288

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BZ16288

Product Name :Phospho-PTEN (Ser380) polyclonal antibody

Swiss-Prot :P60484

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC-P,ICC/IF

Application_all :IHC: 1/50-1/100 ICC: 1/100-1/200

Background :Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :-

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog

Immunogen :Synthetic peptide of human PTEN

Conjugate :Unconjugated

Modification :Phosphorylated

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Phospho-PTEN antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample with blocking peptide on the right.

Immunofluorescence analysis of Phospho-PTEN in Hela cells using PTEN antibody,and DAPI .