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LAT polyclonal antibody

货号: BZ16220

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16220

Product Name :LAT polyclonal antibody

Swiss-Prot :O43561

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,ELISA

Application_all :WB: 1/500-1/1000 ELISA: 1/10000

Background :Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 28 kDa; Observed MW: 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LAT; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; pp36; p36-38

Immunogen :Synthesized peptide derived from LAT . at AA range: 190-270

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LAT in 293 lysates using LAT antibody.

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