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Wnt1 polyclonal antibody

货号: BZ16122

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16122

Product Name :Wnt1 polyclonal antibody

Swiss-Prot :P04628

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC-F,IHC-P,ICC/IF,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :WNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 41 kDa; Observed MW: 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :WNT1; INT1; Proto-oncogene Wnt-1; Proto-oncogene Int-1 homolog

Immunogen :The antiserum was produced against synthesized peptide derived from human WNT1. AA range:301-350

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Wnt1 in various lysates using Wnt1 antibody.

免疫沉淀（IP）