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Phospho-IGF1 Receptor (Tyr1165/Tyr1166) polyclonal antibody

货号: BZ16111

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16111

Product Name :Phospho-IGF1 Receptor (Tyr1165/Tyr1166) polyclonal antibody

Swiss-Prot :P08069

Host :Rabbit

Reactivity :Human,Mouse,Rat,Monkey

Applications :WB,ELISA

Application_all :WB: 1/500-1/1000 ELISA: 1/10000

Background :This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 155 kDa; Observed MW: 155 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Immunogen :The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166. AA range:1131-1180

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-IGF1 Receptor in various lysates using Phospho-IGF1 Receptor antibody.