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Phospho-IRS1 (Ser636) polyclonal antibody

货号: BZ16044

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BZ16044

Product Name :Phospho-IRS1 (Ser636) polyclonal antibody

Swiss-Prot :P35568

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 132 kDa; Observed MW: 150 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IRS1; Insulin receptor substrate 1; IRS-1

Immunogen :The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636. AA range:603-652

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-IRS1 in SH-SY5Y lysates using Phospho-IRS1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human brain using Phospho-IRS1 antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval. Sample with blocking peptide on the right.