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Perforin polyclonal antibody

货号: BZ16042

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16042

Product Name :Perforin polyclonal antibody

Swiss-Prot :P14222

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background :The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 61 kDa; Observed MW: 61 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Perforin-1; P1; Cytolysin; Lymphocyte pore-forming protein; PFP

Immunogen :The antiserum was produced against synthesized peptide derived from the C-terminal region of human PRF1. AA range:451-500

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Perforin in Hela lysates using Perforin antibody.

Immunohistochemistry analysis of paraffin-embedded Human kidney using Perforin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.