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TGF beta 1 polyclonal antibody

货号: BS91338

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS91338

Product Name :TGF beta 1 polyclonal antibody

Swiss-Prot :P01137

Host :Rabbit

Reactivity :Mouse, Rat

Applications :IF/ICC

Application_all :IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :Refer to figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TGFB1;CED;DPD1;LAP;TGFB;TGFbeta;TGF-β

Immunogen :Recombinant fusion protein of human TGF beta 1(NP_000651.3).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of NIH/3T3 cells using TGF beta 1 Rabbit pAb at dilution of 1:100 . Blue: DAPI for nuclear staining.

Pep27 Mutant Immunization Inhibits Caspase-14 Expression to Alleviate Inflammatory Bowel Disease via Treg Upregulation

JournalMicroorganisms

ApplicationWB

IF4.926

SpeciesMouse

PMID36144473
Simiao pill inhibits epithelial mesenchymal transition in a mouse model of chronic hyperuricemic nephropathy by inhibiting NLRP3 inflammasome activation

JournalBMC Complementary Medicine and Therapies

ApplicationWB

IF2.838

SpeciesMouse

PMID36271349
Imidazo[1,2-a]pyridine Derivatives as AMPK Activators: Synthesis, Structure–Activity Relationships, and Regulation of Reactive Oxygen Species in Renal Fibroblasts

JournalChemMedChem

ApplicationWB

IF3.54

SpeciesRat

PMID36750404
Effect of artesunate on cardiovascular complications in periodontitis in a type I diabetes rat model and related mechanisms

JournalJOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

ApplicationIHC

IF5.467

SpeciesRat

PMID36892740
Effects and mechanisms of long-acting glucagon-like peptide-1 receptor agonist semaglutide on microglia phenotypic transformation and neuroinflammation after cerebral ischemia/reperfusion in rats

Journal10.4103/bc.bc_38_24

ApplicationWB

IF2.3

SpeciesRat

PMID