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ATRIP polyclonal antibody

货号: BS8739

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8739

Product Name :ATRIP polyclonal antibody

Swiss-Prot :Q8WXE1

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF ICC

Application_all :WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:200 ICC 1:50 - 1:200

Background :The product of the ATRIP gene is an essential component of the DNA damage checkpoint, and binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ATRIP polyclonal antibody detects endogenous levels of ATRIP protein.

BiowMW :~ 95 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATR-interacting protein; ATM and Rad3-related-interacting protein; ATRIP; AGS1

Immunogen :Synthetic peptide, corresponding to Human ATRIP.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ATRIP expression in Jurkat (A) whole cell lysates.

Immunohistochemical analysis of ATRIP staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of ATRIP staining in MCF-7 cells.

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