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STING/TMEM173 polyclonal antibody

货号: BS80431

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS80431

Product Name :STING/TMEM173 polyclonal antibody

Swiss-Prot :Q3TBT3

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IHC-P

Application_all :WB 1:500-1:1000 IHC-P 1:50-1:200

Background :This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :STING/TMEM173 polyclonal antibody detects endogenous levels of STING/TMEM173 protein.

BiowMW :~ 33, 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ERIS; MPYS; Mita; STING; Tmem173; STING-beta; 2610307O08Rik

Immunogen :A synthetic peptide corresponding to a sequence within amino acids 280-371 of mouse STING. (NP_938023.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of various lysates using STING pAb at 1:1000 dilution.

Immunohistochemistry analysis of STING in paraffin-embedded human colon carcinoma using STING pAb at dilution of 1:20 (40x lens).

Immunohistochemistry analysis of STING in paraffin-embedded rat spleen using STING pAb at dilution of 1:20 (40x lens).

Immunohistochemistry analysis of STING in paraffin-embedded mouse spleen using STING pAb at dilution of 1:20 (40x lens).