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TIM-3/HAVCR2 polyclonal antibody

货号: BS80406

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS80406

Product Name :TIM-3/HAVCR2 polyclonal antibody

Swiss-Prot :Q8TDQ0

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200

Background :The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TIM-3/HAVCR2 polyclonal antibody detects endogenous levels of TIM-3/HAVCR2 protein.

BiowMW :45-70kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HAVCR2;CD366;HAVcr-2;KIM-3;TIM3;TIMD-3;TIMD3;Tim-3

Immunogen :Recombinant fusion protein containing a sequence corresponding to amino acids 22-202 of human TIM-3/HAVCR2 (NP_116171.3).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of various lysates using TIM-3/HAVCR2 pAb at 1:1000 dilution.

Immunohistochemistry of paraffin-embedded human lung cancer using TIM-3/HAVCR2 antibody at dilution of 1:100 .

Immunohistochemistry of paraffin-embedded mouse spleen using TIM-3/HAVCR2 antibody at dilution of 1:100 .

免疫沉淀（IP）