Product Name :[KO Validated] FGF2 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB,1:500 - 1:2000
Background :The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Unmodification
BiowMW :18KDa/22KDa/24KDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :FGF2; BFGF; FGF-2; FGFB; HBGF-2; fibroblast growth factor 2
Immunogen :A synthetic peptide of human FGF2(NP_001997.5).
Modification :Unmodification
