Product Name :[KO Validated] BRD4 polyclonal antibody
Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200
Background :The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Unmodification
BiowMW :200KDa/140KDa/120KDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BRD4;CAP;HUNK1;HUNKI;MCAP;BRD4 short isoform
Immunogen :A synthetic peptide of human BRD4 (NP_055114.1).
Modification :Unmodification