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FLG polyclonal antibody

货号: BS80239

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS80239

Product Name :FLG polyclonal antibody

Swiss-Prot :P20930

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IHC IF/ICC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF/ICC: 1:50~1:200

Background :The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FLG polyclonal antibody detects endogenous levels of FLG protein.

BiowMW :~ 435 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Filaggrin

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human FLG.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of FLG expression in Myla2059 (A) whole cell lysates.

Immunohistochemical analysis of FLG staining in human skin formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of FLG staining in BV2 cells.

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